CHLORPROMAZINE, HALOPERIDOL, METOCLOPRAMIDE AND DOMPERIDONE RELEASE PROLACTIN THROUGH DOPAMINE ANTAGONISM AT LOW CONCENTRATIONS BUT PARADOXICALLY INHIBIT PROLACTIN RELEASE AT HIGH CONCENTRATIONS
نویسندگان
چکیده
منابع مشابه
Prolactin concentrations during anaesthesia.
intestine is normal with no evidence of malabsorption." Three-day faecal fat excretion and xylose absorption test were normal. Although the serum B12 level was not available at the time, the evidence from blood, marrow, and barium meal examinations suggested vitamin B12 deficiency due to pernicious anaemia, and treatment was started with hydroxocobalamin 1 mg intramuscularly daily for four days...
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Hypothalamic dopamine neurons inhibit pituitary prolactin secretion. In this issue of Neuron, Lyons et al. provide evidence for a novel model, whereby the excitatory neuropeptide TRH depolarizes gap-junction-coupled dopamine neurons, leading to a shift in the population pattern of action potentials from phasic burst firing to regular tonic firing, hypothetically reducing dopamine release while ...
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We measured basal plasma prolactin concentrations (in samples obtained during the early follicular phase) in 25 normal (control) women and in a similar group of 40 patients with a long-standing history of infertility. The infertile patients were all ovulating regularly, and had been unsuccessfully treated with clomiphene and in some cases dydrogesterone and human menopausal gonadotrophin. Altho...
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Serial plasma prolactin levels were measured following eighteen generalised seizures, ten partial seizures and eight pseudoseizures. Prolactin levels were elevated following generalised seizures, but were normal following the other seizure types. Plasma prolactin levels may, therefore, be helpful in differentiating between generalised and pseudoseizures. The optimal time for estimating the prol...
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Dopamine is a naturally occurring catecholamine with actions in the central nervous system and endocrine systems, including inhibition of prolactin release from the pituitary gland. Prolactin secretion has been shown to be increased in response to physiological stress, while hypoprolactinaemia is associated with a reduction in the cellular immune response. We have investigated the effects of lo...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1980
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1980.tb10974.x